LIFE SCIENCES & MATERIALS

CRISPR guide RNA design & off-target checks

Task and verification

Design Cas9/Cas12 single-guide RNAs (sgRNA) for target gene knockouts with systematic evaluation of off-target cleavage risks across the full reference genome.

Tools and runtime

Bowtie + Cas-OFFinder + reference genome sequence indexing

OPENENV / CRISPR

Plan a training run

Check the environment’s availability, compatible models and compute in Studio. A catalog entry does not guarantee that hosted training is enabled for your workspace.